Spinal Cord Injury: Use of Stem Cells Regenerate Vital Motor Structures in Mice
A collaboration of researchers at the University of California-San Diego School of Medicine and the Veterans Affairs San Diego Healthcare System have successfully used stem cells to regenerate damaged spinal cords in paralyzed mice.
Senior author Dr. Mark Tuszynski, PhD and his team selected omnipotent stem cells to grow vital corticospinal axons required to carry out voluntary movements in different organisms, including humans. The stem cells were injected into the injury sites of mice with spinal cord lesions. The study showed that the cells regenerated lost tissue and reformed synapses that allowed the mice to regain motor function in their limbs.
This was the first time neural stem cells were used to regenerate vital spinal cord structures, encouraging the possibility of therapeutic application in larger organisms and humans. Recent reported studies have also used stem cells to reform lesioned bone matrix in mice with osteoporosis. For more information on that clinical study, click here.
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